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Anti-MEF2A Antibody BHA11300395
Alternative: Myocyte-specific enhancer factor 2A|Serum response factor-like protein 1|MEF2A|MEF2
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 15q26.3
Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human MEF-2.
Description: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.
TARGETWeight: 55 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: MEF2A (P313) polyclonal antibody detects endogenous levels of MEF2A protein.
Description: Immunohistochemistry (IHC) analyzes of MEF-2 (P313) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.