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Anti-KRT5 Antibody BHA11300378
Alternative: Keratin, type II cytoskeletal 5|58 kDa cytokeratin|Cytokeratin-5|Cytokeratin5|Short name=CK-5|CK5|Keratin-5|Keratin5|Keratin 5|Short name=K5|Type-II keratin Kb5|KRT5
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 12q13.13
Immunogen: Synthetic peptide, corresponding to amino acids 550-600 of Human Cytokeratin 5.
Description: Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).
TARGETWeight: 62 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: Cytokeratin 5 (S573) polyclonal antibody detects endogenous levels of Cytokeratin 5 protein.
Description: Western blot (WB) analysis of Cytokeratin 5 (S573) polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate(40ug)Lane2:PC12 whole cell lysate(40ug)Lane3:NIH-3T3 whole cell lysate(40ug)
Description: Immunohistochemistry (IHC) analyzes of Cytokeratin 5 (S573) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.