ebiohippo is a top distributor of the best and most reliable ELISA and Assay kits. We can provide a wide range of kits from well-known suppliers and brands with authentic and validated data. We provide antibodies to help you quickly identify and quantify proteins, and evaluate other necessary data for various applications in life sciences.
Anti-JUN Antibody BHA11300242
Alternative: JUN|p39|V-jun avian sarcoma virus 17 oncogene homolog|Proto-oncogene c-Jun|AP1|Activator protein 1|Transcription factor AP-1
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 1p32.1
Immunogen: Synthetic peptide, corresponding to amino acids 201-250 of Human c-Jun.
Description: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
TARGETWeight: 43, 48 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: c-Jun (N57) polyclonal antibody detects endogenous levels of c-Jun protein.
Description: Western blot (WB) analysis of c-Jun (N57) pAb at 1:500 dilutionLane1:HEK293T whole cell lysate(40ug)Lane2:H9C2 whole cell lysate(40ug)Lane3:CT26 whole cell lysate(40ug)Lane4:A549 whole cell lysate(40ug)