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Anti-AR Antibody BHA11300201
Alternative: Androgen receptor|Dihydrotestosterone receptor|Nuclear receptor subfamily 3 group C member 4|AR|DHTR|NR3C4
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: primary antibodies|polyclonal antibodies
Chromosome Location: Xq12
Immunogen: Synthetic peptide, corresponding to amino acids 611-660 of Human AR.
Description: Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.
TARGETWeight: 110 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: AR (E646) polyclonal antibody detects endogenous levels of Androgen Receptor protein.
Description: Immunohistochemistry (IHC) analyzes of AR (E646) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.