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Anti-PIK3C3 Antibody BHA11300153
Alternative: Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog|ATG1|Unc-51-like kinase 1|ULK1|KIAA0722
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 18q12.3
Immunogen: Synthetic peptide, corresponding to amino acids 700-800 of Human ULK1.
Description: ULK1 and ULK2 (for UNC-51-like kinase) encode similar amino-terminal serine/threonine kinase domains, a proline/serine-rich (PS) domain, and a species conserved carboxyl-terminal domain. Both share homology with the UNC-51 kinase from Caenorhabditis elegans and the APG1 kinase in yeast, which are involved in axonal extension and growth, and autophagy, respectively. ULK1 and ULK2 are thought to auto-phosphorylate the PS domain in vitro, and the significant homology among vertebrates suggest that ULK1 and ULK2 are involved in the regulation of fundamental biological processes.
TARGETWeight: 150 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: ULK1 (S757) polyclonal antibody detects endogenous levels of ULK1 protein.
Description: Western blot (WB) analysis of ULK1 (S757) polyclonal antibody at 1:500 dilutionLane1:L02 whole cell lysate(40ug)Lane2:Panc1 whole cell lysate(40ug)Lane3:C6 whole cell lysate(40ug)Lane4:AML-12 whole cell lysate(40ug)