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Anti-Calmodulin Antibody BHA11300132
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: primary antibodies|polyclonal antibodies
Chromosome Location: 4p15.2
Immunogen: A synthetic peptide corresponding to residues in Human PRGC1.
Description: PPARγ coactivator-1α (PGC-1α) was originally identified as a transcriptional coactivator whose expression closely correlated with adaptive thermogenesis following exposure to cold temperatures. Named for its association with the nuclear receptor peroxisome-proliferator activated receptor (PPARγ), PGC-1α interacts with a diverse array of transcription factors to regulate numerous aspects of cell physiology. PGC-1α helps to regulate cell processes important in adaptive thermogenesis and energy metabolism, including the related functions of glucose uptake, gluconeogenesis, insulin secretion, and mitochondrial biogenesis. Long thought to be a potential therapeutic target for the treatment of type II diabetes, obesity, cardiomyopathy, or other metabolic disorders, a recent functional survey found no obvious differences in PPARγ activity associated with recognized PGC-1α variants.
TARGETWeight: 91 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.Specificity: PRGC1 (K87) polyclonal antibody detects endogenous levels of PRGC1 protein.
Description: Western blot (WB) analysis of PRGC1 (K87) polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate(40ug)Lane2:HepG2 whole cell lysate(40ug)Lane3:A549 whole cell lysate(40ug)Lane4:The Lung tissue lysate of Mouse(40ug)Lane5:The Lung tissue lysate of Rat(40ug)