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Anti-CASP9 Antibody BHA11300031
Alternative: CASP 9|Caspase9|Caspase-9|CASP-9|Apoptotic protease Mch-6|Apoptotic protease-activating factor 3|APAF-3|ICE-like apoptotic protease 6|ICE-LAP6|Caspase-9 subunit p35|Caspase-9 subunit p10|CASP9|MCH6
Species: Homo Sapiens (Human)
Delivery: Free shipping. Usually ships in 7 to 10 business days
Categories: Primary Antibodies|Polyclonal Antibodies
Chromosome Location: 1p36.21
Immunogen: Synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Threonine 125.
Description: Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.
TARGETWeight: 35,48 kDa
PROPERTYStorage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Desc: Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.Specificity: Caspase-9 (phospho-T125) polyclonal antibody detects endogenous levels of Caspase 9 protein only when phosphorylated at Thr125.