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AMG-548 hydrochloride (864249-60-5 free base)

SKU : BHB20401025

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Description
Review(s)

Mfr.No.	T10298
Description	AMG-548 hydrochloride is an orally active and selective p38alpha inhibitor (Ki: 0.5 nM) and shows slightly selective over p38beta (Ki: 36 nM) and >1000 fold selective against p38gamma/p38delta. It is also extremely potent in the inhibition of whole blood LPS stimulated TNFalpha (IC50: 3 nM).
Molecular Formula	C29H28ClN5O
Signaling Pathways	MAPK
Smiles	O=C1N(C)C(NCC(N)CC2=CC=CC=C2)=NC(C3=CC=NC=C3)=C1C4=CC=C5C=CC=CC5=C4.Cl
Molecular Weight	498.02
Target	p38 MAPK

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SKU	Supplier No.	Size	Your price	Quantity
BHB20401025	T10298	100 mg	-		Add to Quote
BHB20401025	T10298	500 mg	-		Add to Quote

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AMG-548 hydrochloride (864249-60-5 free base)

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