17-phenyl trinor Prostaglandin F2? diethyl amide

Mfr.No.	T84653
Description	17-Phenyl trinor Prostaglandin F2alphadiethyl amide (17-phenyl trinor PGF2alphadiethyl amide) is a Prostaglandin F2alpha(PGF2alpha) analog characterized by the substitution of the C-1 carboxyl group with an N-diethyl amide. Prostaglandin (PG) esters and N-ethyl amides have demonstrated ocular hypotensive properties, with N-ethyl amides introduced as alternative options for PG hypotensive prodrugs. Studies indicate that both bovine and human corneal tissues can convert N-ethyl amides of various PGs into their free acid forms at a rate of approximately 2.5 ug/g corneal tissue/hr. However, dialkyl amides like 17-phenyl trinor PGF2alphadiethyl amide resist conversion by corneal amidase, showing no detectable transformation into free acids. This characteristic suggests their potential as valuable investigative tools for assessing the intrinsic intraocular hypotensive activities of PG amides.
Signaling Pathways	Others
Cas Number	1176637-26-5
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20445928	T84653	10 mg	-		Add to Quote
BHB20445928	T84653	50 mg	-		Add to Quote