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Home / Proteins & Peptide

Recombinant Mouse SAM domain and HD domain-containing protein 1(SAMHD1),partial

SKU : BHP10500896

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP020691MO
Alternative Names	Interferon-gamma-inducible protein Mg11SAM domain and HD domain-containing protein 1
Antigen	SAMHD1
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling .
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	395-626aa
Mol Weight	30.6kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Nucleus
Uniprot	Q60710, Q60710
Database Links	KEGG:mmu:56045 STRING:10090.ENSMUSP00000059717 UniGene:Mm.248478
Function	Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling. Has ribonuclease activity, acting on single-stranded RNA.
Protein Families	SAMHD1 family
Research Area	Others
Weight	30.7kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500896	CSB-EP020691MO	1mg	$2466		Add to Cart
BHP10500896	CSB-EP020691MO	100ug	$578		Add to Cart
BHP10500896	CSB-EP020691MO	20ug	$306		Add to Cart

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