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Recombinant Mouse Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1(Lingo1),partial

SKU : BHP10504261

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP880476MO
Alternative Names	Leucine-rich repeat neuronal protein 1Leucine-rich repeat neuronal protein 6A
Antigen	LINGO1
Tag	N-terminal 6xHis-tagged
Description	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.1 Publication
Regulatory	RUO
Relevance	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.1 Publication
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	37-555aa
Mol Weight	62.9kDa
Nature	Recombinant
Protein Description	Partial

Subcellular Location	Cell membrane, Single-pass type I membrane protein
Uniprot	Q9D1T0, Q9D1T0
Database Links	KEGG:mmu:235402 STRING:10090.ENSMUSP00000059050 UniGene:Mm.246605
Function	Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.
Research Area	Others
Tissue Specificity	Highly specific expression in the central nervous system. Predominant expression in neocortex, amygdala, hippocampus, thalamus and entorhinal cortex, with lower levels in cerebellum and basal nuclei.
Weight	62.9 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Mus Musculus (Mouse)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504261	CSB-EP880476MO	1mg	$2466		Add to Cart
BHP10504261	CSB-EP880476MO	100ug	$578		Add to Cart
BHP10504261	CSB-EP880476MO	20ug	$306		Add to Cart

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