EPHA7 is a member of the ephrin receptor subfamily of protein-tyrosine kinases family that have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2-fibronectin types III repeats. EPHA7 mediated signaling act as a physiologic trigger for apoptosis that can alter brain size and shape by regulating the number of neural progenitors . The high expression of EPHA7 protein plays an important role in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma .
Alternative Names
CEK11 ; EHK3 ; HEK11 ; MDK1
Tag
N-GST tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Mouse
Biological Activity Comment
The specific activity of EPHA7 was determined to be35 nmol /min/mg as per activity assay protocol.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.