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Recombinant Human T-lymphocyte activation antigen CD86(CD86),partial (Active)

BHP10506841
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Subcellular Location Cell membrane, Single-pass type I membrane protein
Uniprot P42081
Database Links

HGNC:1705

OMIM:601020

KEGG:hsa:942

STRING:9606.ENSP00000332049

UniGene:Hs.171182
Function Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.; FUNCTION
Pathway Toll-like receptor signaling pathway
Research Area Immunology
Tissue Specificity Expressed by activated B-lymphocytes and monocytes.
Purity Greater than 95% as determined by SDS-PAGE.
Storage Buffer Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.2
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506841 CSB-AP005161HU 1mg $3094
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BHP10506841 CSB-AP005161HU 500ug $2166
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BHP10506841 CSB-AP005161HU 50ug $290
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