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Home / Proteins & Peptide

Recombinant Human Set1/Ash2 histone methyltransferase complex subunit ASH2(ASH2L)

SKU : BHP10501584

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP883363HU
Alternative Names	ASH2-like protein
Antigen	ASH2L
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hatopoiesis.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-534aa
Mol Weight	76.2kDa
Nature	recombinant
Protein Description	Full Length of Isoform 3

Subcellular Location	Nucleus
Uniprot	Q9UBL3, Q9UBL3
Database Links	HGNC:744 OMIM:604782 KEGG:hsa:9070 STRING:9606.ENSP00000340896 UniGene:Hs.521530
Function	Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Research Area	Transcription
Tissue Specificity	Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes.
Weight	76.2kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501584	CSB-EP883363HU	1mg	$1812		Add to Cart
BHP10501584	CSB-EP883363HU	100ug	$419		Add to Cart
BHP10501584	CSB-EP883363HU	20ug	$224		Add to Cart

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