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Home / Proteins & Peptide

Recombinant Human FLT3 Ligand (FLT3LG)

SKU : BHP10900293

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102745
Description	Known to bind to cells that express the tyrosine kinase receptor, FLT3LG promotes long-term expansion and differentiation of human pro-B cells. Human FLT3LG also stimulates the proliferation of cells expressing murine FLT-3 receptors. In combination with SCF and IL3, FLT3LG can cause expansion of cells with the marker spectrum CD34(+)/CD38(-). Alone, FLT3LG supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU-GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. FLT3LG has only marginal effects on progenitors for erythroid cells and megakaryocytes. Recombinant Human FLT3LG expressed from human 293 cells is a monomeric glycoprotein with a molecular mass of 24 to 30 kDa.
Alternative Names	Fms-related tyrosine kinase 3 ligand ; FLT3 ligand ; FLT3LG ; FLT3L
Quantity	10 µg
Regulatory	RUO
Source	HEK293
Host	Human
Endotoxin Level	<1 EU/µg of recombinant protein as determined by the LAL method
Biological Activity Comment	The EC(50) as determined by the dose-dependent stimulation of the proliferation of the human acute myeloid leukemia cell line OCI-AML5 was found to be ≤0.8 ng/mL.

Weight	24 to 30 kDa, monomer, glycosylated

Description	A quick spin of the vial followed by reconstitution in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Format	Lyophilized Powder 1x PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900293	Z102745	10µg	$314.44		Add to Cart

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