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Home / Proteins & Peptide

Recombinant Human FABP4/A-FABP Protein (29 Ala/Thr, His Tag)

SKU : BHP10302841

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030902
Description	A DNA sequence encoding the human FABP4 (P15090) (Cys 2-Ala 132) (29 Ala / Thr) was expressed; with a polyhistide tag at the N-terminus.
Alternative Names	Fatty Acid-Binding Protein Adipocyte; Adipocyte Lipid-Binding Protein; ALBP; Adipocyte-Type Fatty Acid-Binding Protein; A-FABP; AFABP; Fatty Acid-Binding Protein 4; aP2;HEL-S-104
Reconstitution	Please refer to the printed manual for detailed information.
Background	Fatty acid-binding protein; adipocyte; also known as Adipocyte-type fatty acid-binding protein; Fatty acid-binding protein 4; Adipocyte lipid-binding protein; and FABP4; is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL); FABP4 correlated to body mass index (BMI); waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index; triglycerides; HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD; adjusted by age; sex; body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients; and therefore; could serve to guide therapeutic intervention in this group of patients.
Reactivity	Human
Tag	N-His
Formulation	Lyophilized from sterile 50mM Tris; 200mM NaCl; 10% glycerol; pH 8.2
Host	E.coli
Accession Number	P15090
Endotoxin Level	Please contact us for more information.
Mol Weight	16 kDa
Mw(kda)	16 kDa

Sequence Info	Cys 2-Ala 132

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302841	PKSH030902	100ug	$732		Add to Cart

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