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Home / Proteins & Peptide

Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 3(EIF4EBP3)

SKU : BHP10500509

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP007565HU
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Repressor of translation initiation that regulates EIF4E activity by preventing its assbly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-100aa
Mol Weight	26.9kDa
Nature	recombinant
Protein Description	Full Length

Uniprot	O60516, O60516
Database Links	HGNC:3290 OMIM:603483 KEGG:hsa:8637 STRING:9606.ENSP00000308472 UniGene:Hs.594084
Function	Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex
Protein Families	EIF4E-binding protein family
Research Area	Epigenetics and Nuclear Signaling
Tissue Specificity	Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus.
Weight	26.87kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500509	CSB-EP007565HU	1mg	$1812		Add to Cart
BHP10500509	CSB-EP007565HU	100ug	$419		Add to Cart
BHP10500509	CSB-EP007565HU	20ug	$224		Add to Cart

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