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Home / Proteins & Peptide

Recombinant Human Cyclic AMP-responsive element-binding protein 1(CREB1)

SKU : BHP10500444

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP005947HU
Antigen	CREB1
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response elent (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-341aa
Mol Weight	40.7kDa
Nature	recombinant
Protein Description	Full Length

Involvement In Disease	Angiomatoid fibrous histiocytoma (AFH)
Subcellular Location	Nucleus
Uniprot	P16220, P16220
Database Links	HGNC:2345 OMIM:123810 KEGG:hsa:1385 STRING:9606.ENSP00000387699 UniGene:Hs.516646
Function	Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Pathway	cAMP signaling pathway; Estrogen signaling pathway; Melanogenesis; PI3K-Akt signaling pathway; TNF signaling pathway; Antigen processing and presentation; Osteoclast differentiation; Th17 cell differentiation; Thyroid hormone synthesis; AMPK signaling; cGMP-PKG signaling pathway; Glucagon signaling pathway
Protein Families	BZIP family
Research Area	Immunology
Weight	40.8kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500444	CSB-EP005947HU	1mg	$1812		Add to Cart
BHP10500444	CSB-EP005947HU	100ug	$419		Add to Cart
BHP10500444	CSB-EP005947HU	20ug	$224		Add to Cart

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