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Home / Proteins & Peptide

Recombinant Human Cardiotrophin-1 (CT-1)

SKU : BHP10901031

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102369
Description	Cardiotrophin-1 is a pleiotrophic cytokine and is a member of the IL-6 cytokine family that also includes IL6, IL11, LIF, OSM, CLC and IL31.Full length human CT-1 shares a 79% amino acid sequence identity with murinic CT-1 and both lack a canonical signal sequence. Cardiotrophin-1 interacts with the leukemia inhibitory factor receptor (LIFR) heterodimer and the glycoprotein 130 subunit (gp130) and has the ability to induce cardiac myocyte hypertrophy. It is highly expressed in various skeletal muscles and cardiac tissue, as well as the colon, ovary and prostate, liver, and pancreas, while lower expression levels are found in the lungs, kidney, pancreas, testis, and small intestine.
Alternative Names	Recombinant Human Cardiotrophin-1 ; CTF1 ; CT1 ; CT-1
Quantity	1.0 mg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	ED50 is ≤ 0.5 ng/mL as determined by the dose-dependent TF-1 cell proliferation.

Weight	21.0 kDa

Description	Reconstitute in sterile 20mM Tris, pH 8.0 at 100µg/mL (containing at least 0.1% human or bovine serum albumin). Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1–1.0% BSA.
Format	Lyophilized Powder Lyophilized from a 0.2 µm filtered solution in PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901031	Z102369	1.0mg	$1115		Add to Cart

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