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Home / Proteins & Peptide

Recombinant Chicken Transforming growth factor beta-1 proprotein(TGFB1),partial

SKU : BHP10500971

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP023446CH
Antigen	TGFB1
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of th have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone rodeling. It is a potent stimulator of osteoblastic bone formation, causing chotaxis, proliferation and differentiation in committed osteoblasts .
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	260-373aa
Mol Weight	29.0kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Secreted
Uniprot	P09531, P09531
Database Links	UniGene:Gga.929
Function	Multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodeling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Mediates SMAD2/3 activation by inducing its phosphorylation and subsequent translocation to the nucleus (By similarity).
Pathway	Hippo signaling pathway; MAPK signaling pathway; TGF-beta signaling pathway; Cell cycle; Cellular senescence; Osteoclast differentiation; Th17 cell differentiation; AGE-RAGE signaling pathway in diabetic complications; FoxO signaling pathway
Protein Families	TGF-beta family
Research Area	Others
Weight	29kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Gallus Gallus (Chicken)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500971	CSB-EP023446CH	1mg	$2466		Add to Cart
BHP10500971	CSB-EP023446CH	100ug	$729		Add to Cart
BHP10500971	CSB-EP023446CH	20ug	$388		Add to Cart

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