Human JAM-A Protein, hFc Tag

Mfr.No.	PME100554
Description	Recombinant Human JAM-A Protein with C-terminal human Fc tag
Background	Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serVIng as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reoVIrus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatIVely spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Tag	C-Human Fc tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 49.1 kDa after removal of the signal peptide.The apparent molecular mass of JAM-A-hFc is approXimately 55-70 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price
BHP18100412	PME100554	100 ug	$340	Add to Cart
BHP18100412	PME100554	50 ug	$230	Add to Cart
BHP18100412	PME100554	10 ug	$60	Add to Cart