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Animal Model

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Il1b-Luc-Tg

    Il1b-Luc-Tg

    • Description : The transgenic
    • Nomenclature : B6.Cg-Tg(IL1B-l
    • Strain : Repository Live
    • KI/KO Gene : IL1B
    • Synonyms : Il-1b; IL-1bet
  • Il1b-Luc-2A-EGFP

    Il1b-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : IL1B
    • Synonyms : Il-1b; IL-1bet
  • Il1a-Luc-2A-EGFP

    Il1a-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : Il1a
    • Synonyms : Il-1a
  • Il5-Luc-2A-EGFP

    Il5-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il5
    • Strain : Embryo cryopres
    • KI/KO Gene : Il5
    • Synonyms : Il-5
  • Il23a-Luc-2A-EGFP

    Il23a-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Embryo cryopres
    • KI/KO Gene : Il23a
    • Synonyms : p19 IL-23
  • Il1f6-Luc-2A-EGFP

    Il1f6-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : Il1f6
    • Synonyms : Fil1 IL-1H1 IL1
  • Itgax-tdTomato-Luc

    Itgax-tdTomato-Luc

    • Description : A IRES-tdTomat
    • Nomenclature : C57BL/6Smoc-Itg
    • Strain : Embryo cryopres
    • KI/KO Gene : Itgax
    • Synonyms : Cr4; N418; Cd11
  • Itgax-IRES-DTRGFP

    Itgax-IRES-DTRGFP

    • Description : A IRES-DTREGFP
    • Nomenclature : C57BL/6Smoc-Itg
    • Strain : Embryo cryopres
    • KI/KO Gene : Itgax
    • Synonyms : Cr4; N418; Cd11
  • MHC Class II(I-A/I-E)-KO(Nod-Scid)

    • Description : All sequences f
    • Nomenclature : NOD-PrkdcscidH2
    • Strain : Developing
    • KI/KO Gene : H2-Ab1
    • Synonyms : IAb; Ia2; Ia-2;
  • MHC Class II (I-A/I-E) -KO

    • Description : All sequences f
    • Nomenclature : C57BL/6Smoc-H2-
    • Strain : Repository Live
    • KI/KO Gene : H2-Ab1
    • Synonyms : IAb; Ia2; Ia-2;
  • Ly6g-2A-DTRGFP(BALB/c)

    Ly6g-2A-DTRGFP(BALB/c)

    • Description : 2A-DTRGFP expre
    • Nomenclature : BALB/cAnSmoc-Ly
    • Strain : Repository Live
    • KI/KO Gene : Ly6g
    • Synonyms : Gr1; Gr-1; Ly-6
  • Pdcd1-DTR-2A-tdTomato

    Pdcd1-DTR-2A-tdTomato

    • Description : A DTR-2A-tdToma
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1, Pdc1, Ly1
  • NVG-hIL15

    NVG-hIL15

    • Description : The endogenous
    • Nomenclature : NOD.Cg-Prkdcsci
    • Strain : Embryo cryopres
    • KI/KO Gene : Il15
    • Synonyms : IL-15; AI503618
  • NMG

    NMG

    NMG

    • Description : Prkdc and Il2rg
    • Nomenclature : NOD.Cg-Prkdcsci
    • Strain : Repository Live
    • KI/KO Gene : Il2rg
    • Synonyms : gc p64 (g)c CD1
  • Ncr1-IRES-mtagBFP2-Luc

    Ncr1-IRES-mtagBFP2-Luc

    • Description : A IRES-mtagBFP
    • Nomenclature : C57BL/6Smoc-Ncr
    • Strain : Embryo cryopres
    • KI/KO Gene : Ncr1
    • Synonyms : Ly94; NKp46
  • R26-SA-LSL-DTR-IRES-tdTomato

    • Description : A SA-LSL-DTR-IR
    • Nomenclature : C57BL/6Smoc-Gt(
    • Strain : Sperm cryoprese
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26,ROSA26,AV25
  • hSIGLEC15(BALB/c)

    hSIGLEC15(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Si
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Siglec15
  • hSERPINC1

    hSERPINC1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Se
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Serpinc1
  • hSIRPA(2)/hCD47/hPD-1

    hSIRPA(2)/hCD47/hPD-1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Si
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Pdcd1
  • hSIRPA(2)/hCD47/hCTLA-4

    hSIRPA(2)/hCD47/hCTLA-4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Si
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : CTLA4
  • hSIRPA(2)

    hSIRPA(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Si
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Sirpa
  • hSOST

    hSOST

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-So
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Sost
  • hSNCA

    hSNCA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sn
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Snca
  • hSLC7A5

    hSLC7A5

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Slc7a5
  • hSTING(BALB/c)

    hSTING(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-tm
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Tmem173