• Alternative Names :
• Toll-like receptor 10 (CD antigen CD290), TLR10

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Toll-like receptor 10 protein (20-270AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Membrane, Single-pass type I membrane protein

• Uniprot :
• Q9BXR5

• Database Links :
• 
  

  HGNC:15634

  OMIM:606270

  KEGG:hsa:81793

  STRING:9606.ENSP00000308925

  UniGene:Hs.120551

• Function :
• Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

• Protein Families :
• Toll-like receptor family

• Research Area :
• Immunology

• Tissue Specificity :
• Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :