KIAA1031; ROXN; Rotavirus X associated non-structural protein; Z3H7B; ZC3H7B
Antigen
ZC3H7B
Categories
Primary Antibodies
Clonality
polyclonal
Description
a tetratricopeptide (TPR) protein containing 5 zinc fingers. Interacts with the rotavirus non-structural protein NSP3. TPR proteins are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control, mitochondrial and peroxisomal protein transport, neurogenesis and protein folding.Ota T., Nat. Genet. 36:40-45(2004).Rush J., Nat. Biotechnol. 23:94-101(2005).Kikuno R., DNA Res. 6:197-205(1999).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ZC3H7B.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
a tetratricopeptide (TPR) protein containing 5 zinc fingers. Interacts with the rotavirus non-structural protein NSP3. TPR proteins are involved in a variety of biological processes, such as cell cycle regulation, transcriptional control, mitochondrial and peroxisomal protein transport, neurogenesis and protein folding.
Ota T., Nat. Genet. 36:40-45(2004). Rush J., Nat. Biotechnol. 23:94-101(2005). Kikuno R., DNA Res. 6:197-205(1999).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ZC3H7B protein.
May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 'ATA(A/T)' motif in the apical loop.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.