Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.The MGC Project Team; The MGC Project Team;Bunkoczi G., Submitted (SEP-2005) to the PDB data bank.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human ZADH2.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
The MGC Project Team; The MGC Project Team; Bunkoczi G., Submitted (SEP-2005) to the PDB data bank.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total ZADH2 protein.
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficienty towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.