v-SNARE; Vesicle transport through interaction with t-SNAREs homolog 1B; vesicle transport through interaction with t-SNAREs homolog 1B (yeast); Vesicle transport v-SNARE protein Vti1-like 1; vesicle-associated soluble NSF attachment protein receptor
Categories
Primary Antibodies
Clonality
polyclonal
Description
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.Fischer von Mollard G., J. Biol. Chem. 273:2624-2630(1998).Li H.-C., Biochem. Biophys. Res. Commun. 247:70-74(1998).
Host
Rabbit
Immunogen
Synthesized peptide derived from N-terminal of Human VTI1B.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Fischer von Mollard G., J. Biol. Chem. 273:2624-2630(1998). Li H.-C., Biochem. Biophys. Res. Commun. 247:70-74(1998).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total VTI1B protein.
Subcellular Location
Early endosome membrane, Single-pass type IV membrane protein, Late endosome membrane, Single-pass type IV membrane protein, Lysosome membrane, Cytoplasmic granule, Recycling endosome membrane, Single-pass type IV membrane protein
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Protein Families
VTI1 family
Tissue Specificity
Expressed in all tissues examined.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.