Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.Partanen J., Mol. Cell. Biol. 12:1698-1707(1992).Partanen J.M., Submitted (JUL-1993) to the EMBL/GenBank/DDBJ databases.Zhang Z., Protein Sci. 13:2819-2824(2004).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human TIE1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
Partanen J., Mol. Cell. Biol. 12:1698-1707(1992). Partanen J.M., Submitted (JUL-1993) to the EMBL/GenBank/DDBJ databases. Zhang Z., Protein Sci. 13:2819-2824(2004).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total TIE1 protein.
Subcellular Location
Cell membrane, Single-pass type I membrane protein