TBC1 domain family member 3; Rab GTPase-activating protein PRC17; Prostate cancer gene 17 protein; TRE17 alpha protein; TBC1D3
Antigen
TBC1D3
Categories
Primary Antibodies
Clonality
polyclonal
Description
Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.Pei L., Cancer Res. 62:5420-5424(2002).Wiemann S., Genome Res. 11:422-435(2001).Onno M., DNA Cell Biol. 12:107-118(1993).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human TBC1D3.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.
Pei L., Cancer Res. 62:5420-5424(2002). Wiemann S., Genome Res. 11:422-435(2001). Onno M., DNA Cell Biol. 12:107-118(1993).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total TBC1D3 protein.
Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.
Tissue Specificity
Expressed in liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, small intestine and peripheral blood leukocytes. Overexpressed in prostate cancers.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.