OATP; OATP-A; OATP1; OATP1A2; organic anion transporting polypeptide A
Antigen
SLCO1A2
Categories
Primary Antibodies
Clonality
polyclonal
Description
Mediates the Na+-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids By similarity. Selectively inhibited by the grapefruit juice component naringin.Kullak-Ublick G.-A., Gastroenterology 109:1274-1282(1995).Koenig J., J. Biol. Chem. 275:23161-23168(2000).Lee W., J. Biol. Chem. 280:9610-9617(2005).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human SLCO1A2.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Mediates the Na+-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids By similarity. Selectively inhibited by the grapefruit juice component naringin.
Kullak-Ublick G.-A., Gastroenterology 109:1274-1282(1995). Koenig J., J. Biol. Chem. 275:23161-23168(2000). Lee W., J. Biol. Chem. 280:9610-9617(2005).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total SLCO1A2 protein.
Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin.
Protein Families
Organo anion transporter (TC 2.A.60) family
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.