This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of Human solute carrier family 5 (sodium/glucose cotransporter), member 1
Involvement In Disease
Congenital glucose/galactose malabsorption (GGM)
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total SLC5A1 protein.