Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.Puder M., Biochim. Biophys. Acta 1216:134-136(1993).Yoshihama M., Genome Res. 12:379-390(2002).Odintsova T.I., J. Protein Chem. 22:249-258(2003).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human RPL18.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Puder M., Biochim. Biophys. Acta 1216:134-136(1993). Yoshihama M., Genome Res. 12:379-390(2002). Odintsova T.I., J. Protein Chem. 22:249-258(2003).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total RPL18 protein.