Ras and Rab interactor 3; Ras interaction/interference protein 3; RIN3;
Antigen
RIN3
Categories
Primary Antibodies
Clonality
polyclonal
Description
Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.Heilig R., Nature 421:601-607(2003).Ota T., Nat. Genet. 36:40-45(2004).Saito K., J. Biol. Chem. 277:3412-3418(2002).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human RIN3.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.
Heilig R., Nature 421:601-607(2003). Ota T., Nat. Genet. 36:40-45(2004). Saito K., J. Biol. Chem. 277:3412-3418(2002).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total RIN3 protein.
Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.
Protein Families
RIN (Ras interaction/interference) family
Tissue Specificity
Widely expressed.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.