autoantigen p542; hnRNP associated with lethal yellow homolog; P542; RNA-binding protein Raly;
Antigen
Raly
Categories
Primary Antibodies
Clonality
polyclonal
Description
Probable-RNA binding protein. Could be a heterogeneous nuclear ribonucleoprotein (hnRNP). May be involved in pre-mRNA splicing By similarity.Khrebtukova I., Biochim. Biophys. Acta 1447:107-112(1999).Rhodes G.H., J. Autoimmun. 10:447-454(1997).Deloukas P., Nature 414:865-871(2001).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human RALY.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Probable-RNA binding protein. Could be a heterogeneous nuclear ribonucleoprotein (hnRNP). May be involved in pre-mRNA splicing By similarity.
Khrebtukova I., Biochim. Biophys. Acta 1447:107-112(1999). Rhodes G.H., J. Autoimmun. 10:447-454(1997). Deloukas P., Nature 414:865-871(2001).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total RALY protein.
RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (By similarity). May be a heterogeneous nuclear ribonucleoprotein (hnRNP)
Protein Families
RRM HNRPC family, RALY subfamily
Tissue Specificity
Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.