May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.McBride K, et al. (1998) Mol Cell Biol 18(9): 5073-5081.Williams AJ, et al. (2003) Plant Physiol 132(4): 2086-2097.Wilson MA, et al. (1997) Biochem J 325(Pt 1): 217-222.Arnesen T, et al. (2005) Biochem J 386(Pt 3): 433-443.
Host
Rabbit
Immunogen
Peptide sequence around phosphorylation site of serine 235/236 (R-L-S(p)-S(p)-L-R) derived from Human S6 Ribosomal Protein.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
McBride K, et al. (1998) Mol Cell Biol 18(9): 5073-5081. Williams AJ, et al. (2003) Plant Physiol 132(4): 2086-2097. Wilson MA, et al. (1997) Biochem J 325(Pt 1): 217-222. Arnesen T, et al. (2005) Biochem J 386(Pt 3): 433-443.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous level of S6 Ribosomal Protein only when phosphorylated at serine 235/236.
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.