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Home / Primary Antibodies

Phospho-PRKAR2B (Ser113) Antibody

SKU : BHA10560169

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA039825
Alternative Names	KAP3; PRKAR2B; PKA R2-beta;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.Levy F.O., Mol. Endocrinol. 2:1364-1373(1988).DeGiorgis J.A., J. Proteome Res. 4:306-315(2005).Han G., Proteomics 8:1346-1361(2008)
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of Serine113(R-R-A(p)-S-V) derived from Human PKA-R2β.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.Levy F.O., Mol. Endocrinol. 2:1364-1373(1988).DeGiorgis J.A., J. Proteome Res. 4:306-315(2005).Han G., Proteomics 8:1346-1361(2008)
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of PKA-R2β only when phosphorylated at serine 113.
Subcellular Location	Cytoplasm, Cell membrane

Uniprot	P31323
Database Links	HGNC:9392 OMIM:176912 KEGG:hsa:5577 STRING:9606.ENSP00000265717 UniGene:Hs.433068
Function	Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Pathway	Insulin signaling pathway
Protein Families	CAMP-dependent kinase regulatory chain family
Tissue Specificity	Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560169	CSB-PA039825	100ul	$360		Add to Cart

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