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Home / Primary Antibodies

Phospho-MARCKS (Ser158) Antibody

SKU : BHA10560400

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA876118
Alternative Names	MACS; MARCS; PKCSL; PRKCSL; Protein kinase C substrate
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.Pariser H, et al. Proc Natl Acad Sci U S A 2005 Aug 30; 102(35): 12407-12412Nagumo H, et al. Biochem Biophys Res Commun 2001 Jan 26; 280(3): 605-609Yamamoto H, et al. Arch Biochem Biophys 1998 Nov 15; 359(2): 151-159
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of serine 158 (R-F-S(p)-F-K) derived from Human MARCKS.
Raised In	Rabbit
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Relevance	MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. Pariser H, et al. Proc Natl Acad Sci U S A 2005 Aug 30; 102(35): 12407-12412 Nagumo H, et al. Biochem Biophys Res Commun 2001 Jan 26; 280(3): 605-609 Yamamoto H, et al. Arch Biochem Biophys 1998 Nov 15; 359(2): 151-159
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous level of MARCKS only when phosphorylated at serine 158.
Subcellular Location	Cytoplasm, cytoskeleton, Membrane, Lipid-anchor

Uniprot	P29966
Database Links	HGNC:6759 OMIM:177061 KEGG:hsa:4082 STRING:9606.ENSP00000357624 UniGene:Hs.519909
Function	MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
Pathway	Fc gamma R-mediated phagocytosis
Protein Families	MARCKS family

Buffer	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:1000
IF	1:100-1:200

Tested Application

ELISA,WB,IF;WB:1:500-1:1000,IF:1:100-1:200

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560400	CSB-PA876118	100ul	$360		Add to Cart

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