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Home / Primary Antibodies

Phospho-HCLS1 (Tyr397) Antibody

SKU : BHA10560236

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA258754
Alternative Names	HCLS1; LCKBP1; Hematopoietic cell- specific LYN substrate 1;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression. Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004).
Host	Rabbit
Immunogen	Peptide sequence around phosphorylation site of tyrosine 397(G-D-Y(p)-E-E) derived from Human HS1 .
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression. Kitamura D., Nucleic Acids Res. 17:9367-9379(1989). Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T., Nat. Genet. 36:40-45(2004).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of HS1 only when phosphorylated at tyrosine 397.
Subcellular Location	Membrane, Peripheral membrane protein, Cytoplasm, Mitochondrion

Uniprot	P14317
Database Links	HGNC:4844 OMIM:601306 KEGG:hsa:3059 STRING:9606.ENSP00000320176 UniGene:Hs.14601
Function	Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Tissue Specificity	Expressed only in tissues and cells of hematopoietic origin.

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
Purity	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB

Description

ELISA ; WB, WB ; ELISA

Dilution

WB	1:500-1:1000

Tested Application

ELISA,WB;WB:1:500-1:1000

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10560236	CSB-PA258754	100ul	$360		Add to Cart

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