Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 By similarity.Wehner M., Hum. Genet. 96:616-618(1995).Burwinkel B. Jr., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.Greenman C., Nature 446:153-158(2007).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human PHKG1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 By similarity.
Wehner M., Hum. Genet. 96:616-618(1995). Burwinkel B. Jr., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. Greenman C., Nature 446:153-158(2007).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total PHKG1 protein.
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity).