JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies

NCF1 (Ab-304) Antibody

SKU : BHA10559697

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

CUSABIO TECHONOLOGY LLC

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	CSB-PA046087
Alternative Names	47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-1; NCF-47K; NCF1
Categories	Primary Antibodies
Clonality	polyclonal
Description	NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).Lomax K.J., Science 245:409-412(1989).Rodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990).Gu Y., Exp. Cell Res. 272:62-74(2002).
Host	Rabbit
Immunogen	Synthesized non-phosphopeptide derived from Human Neutrophil Cytosol Factor 1 around the phosphorylation site of serine 304 (R-S-S(p)-I-R).
Involvement In Disease	Granulomatous disease, chronic, cytochrome-b-positive 1, autosomal recessive (CGD1)
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Lomax K.J., Science 245:409-412(1989). Rodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990). Gu Y., Exp. Cell Res. 272:62-74(2002).
Species	Homo Sapiens (Human)
Specificity	The antibody detects endogenous levels of total Neutrophil Cytosol Factor 1 protein.
Subcellular Location	Cytoplasm, cytosol, Membrane, Peripheral membrane protein, Cytoplasmic side

Uniprot	P14598
Database Links	HGNC:7660 OMIM:233700 KEGG:hsa:653361 STRING:9606.ENSP00000289473 UniGene:Hs.647047
Function	NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Pathway	Chemokine signaling pathway Fc gamma R-mediated phagocytosis Leukocyte transendothelial migration Osteoclast differentiation
Tissue Specificity	Detected in peripheral blood monocytes and neutrophils (at protein level).

Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format	liquid
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF, WB ; ELISA ; IF

Dilution

WB	1:500-1:3000
IF	1:100-1:500

Tested Application

ELISA,WB,IF;WB:1:500-1:3000,IF:1:100-1:500

Datasheet
ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10559697	CSB-PA046087	100ul	$297		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.