FLJ21988; Nuclear prelamin A recognition factor- like; PRN; Protein related to Narf;
Antigen
NARFL
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.Wang M., Proc. Natl. Acad. Sci. U.S.A. 91:10591-10595(1994).Van Eynde A., Eur. J. Biochem. 261:291-300(1999).Liu J.P., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human NARFL.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
Wang M., Proc. Natl. Acad. Sci. U.S.A. 91:10591-10595(1994). Van Eynde A., Eur. J. Biochem. 261:291-300(1999). Liu J.P., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total NARFL protein
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
Protein Families
NARF family
Tissue Specificity
Widely expressed.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.