Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity.Hu G.; Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.Devedjiev Y., Structure 8:1137-1146(2000).Zhang Q.-H., Genome Res. 10:1546-1560(2000).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human LYPLA1.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity.
Hu G.; Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases. Devedjiev Y., Structure 8:1137-1146(2000). Zhang Q.-H., Genome Res. 10:1546-1560(2000).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total LYPLA1 protein.
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity.
Protein Families
AB hydrolase superfamily, AB hydrolase 2 family
Weight
24,670 Da
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.