C-type lectin domain family 13 member B; CD205; CLEC13B; DEC-205; gp200-MR6
Antigen
LY75
Categories
Primary Antibodies
Clonality
polyclonal
Description
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment By similarity. Causes reduced proliferation of B-lymphocytes. UniProtKB Q60767McKay P.F., Eur. J. Immunol. 28:4071-4083(1998).Kato M., Immunogenetics 47:442-450(1998).
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human LY75.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment By similarity. Causes reduced proliferation of B-lymphocytes. UniProtKB Q60767
McKay P.F., Eur. J. Immunol. 28:4071-4083(1998). Kato M., Immunogenetics 47:442-450(1998).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total LY75 protein.
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
Tissue Specificity
Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.