LIM domain only protein 3; Neuronal-specific transcription factor DAT1; Rhombotin-3; LMO3; RBTN3
Antigen
LMO3
Categories
Primary Antibodies
Clonality
polyclonal
Description
The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene.Ota T., Nat. Genet. 36:40-45(2004).The MGC Project Team, Genome Res. 14:2121-2127(2004).Foroni L., J. Mol. Biol. 226:747-761(1992).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human LMO3.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene.
Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team, Genome Res. 14:2121-2127(2004). Foroni L., J. Mol. Biol. 226:747-761(1992).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total LMO3 protein.