connexin 37; gap junction protein; alpha 4; 37kDa;
Antigen
GJA4
Categories
Primary Antibodies
Clonality
polyclonal
Description
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.Reed K.E., J. Clin. Invest. 91:997-1004(1993).van Zeijl L., Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.Gregory S.G., Nature 441-315-321(2006).
Host
Rabbit
Immunogen
Synthesized peptide derived from nal of Human GJA4.
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Reed K.E., J. Clin. Invest. 91:997-1004(1993). van Zeijl L., Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. Gregory S.G., Nature 441-315-321(2006).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total GJA4 protein.
Subcellular Location
Cell membrane, Multi-pass membrane protein, Cell junction, gap junction
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Protein Families
Connexin family, Alpha-type (group II) subfamily
Tissue Specificity
Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.