Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.Krueger M., Proc. Natl. Acad. Sci. U.S.A. 97:8566-8571(2000).Ota T., Nat. Genet. 36:40-45(2004).Bechtel S., BMC Genomics 8:399-399(2007).
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human EIF2B3.
Involvement In Disease
Leukodystrophy with vanishing white matter (VWM)
Raised In
Rabbit
Reactivity
Human, Mouse
Regulatory
RUO
Relevance
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Krueger M., Proc. Natl. Acad. Sci. U.S.A. 97:8566-8571(2000). Ota T., Nat. Genet. 36:40-45(2004). Bechtel S., BMC Genomics 8:399-399(2007).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total EIF2B3 protein.