Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.Schaap D., FEBS Lett. 275:151-158(1990).Hart T.C., Mamm. Genome 5:123-124(1994).Hart T.C., Genomics 22:246-247(1994).
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human DGKA.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.
Schaap D., FEBS Lett. 275:151-158(1990). Hart T.C., Mamm. Genome 5:123-124(1994). Hart T.C., Genomics 22:246-247(1994).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total DGKA protein.
Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.
Pathway
Oxidative Phosphorylation Phosphatidylinositol signaling system Phospholipase D signaling pathway
Protein Families
Eukaryotic diacylglycerol kinase family
Tissue Specificity
Lymphocytes and oligodendroglial cells.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Format
liquid
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.