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Home / Primary Antibodies

Desmin Antibody (V9768)

SKU : BHA17119792

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NSJ Bioreagents

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Mfr.No.	V9768, V9768-20UG, V9768-100UG
Clonality	Recombinant Mouse Monoclonal
Description	Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain α-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
Formulation	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Host	Mouse
Immunogen Region	Recombinant human Desmin protein was used as the immunogen for the recombinant Desmin antibody.
Isotype	Mouse IgG1, kappa
Species Reactivity	Human, Mouse, Rat
Note	Optimal dilution of the recombinant Desmin antibody should be determined by the researcher.

Uniprot	P17661

Format	Purified
Purity	Protein G affinity chromatography
Storage	Store the recombinant Desmin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Applications	IHC-P
Description	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17119792-1	V9768-20UG	20ug	$219		Add to Cart
BHA17119792-2	V9768-100UG	100ug	$499		Add to Cart

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