Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha-hydroxylated product.Li-Hawkins J., J. Biol. Chem. 275:16543-16549(2000).Ota T., Nat. Genet. 36:40-45(2004).Mungall A.J., Nature 425:805-811(2003).
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human CYP39A1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha-hydroxylated product.
Li-Hawkins J., J. Biol. Chem. 275:16543-16549(2000). Ota T., Nat. Genet. 36:40-45(2004). Mungall A.J., Nature 425:805-811(2003).
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total CYP39A1protein.