This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen.Clark H.F., Genome Res. 13:2265-2270(2003).Hillier L.W., Nature 434:724-731(2005).Colinge J., Submitted (OCT-2008) to UniProtKB.
Host
Rabbit
Immunogen
Synthesized peptide derived from internal of Human Cytochrome P450 20A1.
Raised In
Rabbit
Reactivity
Human
Regulatory
RUO
Relevance
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen.
Clark H.F., Genome Res. 13:2265-2270(2003). Hillier L.W., Nature 434:724-731(2005). Colinge J., Submitted (OCT-2008) to UniProtKB.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total Cytochrome P450 20A1 protein.