COX; COX-VA; COX5A; Cytochrome c oxidase polypeptide Va; cytochrome c oxidase polypeptide
Antigen
COX5A
Categories
Primary Antibodies
Clonality
polyclonal
Description
This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.Rizzuto R., Gene 69:245-256(1988).Uddin M., BMC Evol. Biol. 8:8-8(2008).Ebert L., Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Host
Rabbit
Immunogen
Synthesized peptide derived from Internal of Human COX5A.
Involvement In Disease
Mitochondrial complex IV deficiency is a rare condition caused by mutation in COX5A that lead to pulmonary arterial hypertension (PAH), failure to thrive and lactic acidemia.
Raised In
Rabbit
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Relevance
This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Rizzuto R., Gene 69:245-256(1988). Uddin M., BMC Evol. Biol. 8:8-8(2008). Ebert L., Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Species
Homo Sapiens (Human)
Specificity
The antibody detects endogenous levels of total COX5Aprotein.